Ciloa has developed the sole technology to produce all types of complex membrane proteins on exosomes. This allows to work with the families of membrane proteins that are called “undruggable”, but that are also the most promising therapeutic targets. Of these are the GPCRs (G-protein coupled receptors), and the ion channels .
Ciloa produces native transmembrane proteins, such as receptors (GPCR, Receptor Kinases), ion channels, transporters, viral envelope proteins. These proteins may have one or several transmembrane domains and can be produced as monomers, homo-oligomers or hetero-oligomers.