Ciloa’s technology targets therapeutic cell exosomes on specific cells to trigger a precise curative action.
Exosomes are natural nano-carriers, perfect for traveling in the human body for delivering new messages. Ciloa’s technology allows to naturally load exosomes with 2 types of proteins: the first one, at the surface, to target the diseased organ; the second one, as a cargo inside the exosome, to deliver a signal (for modification, multiplication or death). The best analogy is a guided missile that recognizes its target and modifies it.
Exosomes can fuse back with cell membranes, introducing new proteins and RNA in new cells. An increasing body of evidence shows that exosomes are natural intercellular shuttle vehicles of materials and of information that can reprogram targeted cells. They are able to pass through any body barriers, including the Blood Brain Barrier.
Ciloa’s genetically engineered exosomes will provide novel innovative vectors for drug delivery.